COL18A1 CLIA Kit for Human(Homo sapiens) | EIAab.comCOL18A1 CLIA Kit for Human(Homo sapiens)

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Index > Protein center > COL18A1(Gene name) > Human

COL18A1 (Gene name),

Collagen alpha-1(XVIII) chain (Protein name ), COIA1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

COL18A1;

Protein name:

Collagen alpha-1(XVIII) chain;

Alternative:

Endostatin;

Organism:

COL18A1 (Homo sapiens).

General Annotation

Sub Unit:

Function:

Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

1754

Sequence:

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1750:

1754:

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3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF01391

KEGG:

hsa:80781

MIM:

120328

UniGene:

Hs.517356

SMR:

P39060

String:

P39060

Uniprot:

P39060

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ELISA Kit for Human Collagen alpha-1(XVIII) chain

Cat.:

E1823h

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Packing:

96T

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ELISA Kit for Human Collagen alpha-1(XVIII) chain

Cat.:

E1823m

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Packing:

96T

CLIA Kit for Human Collagen alpha-1(XVIII) chain

Cat.:

U1823h

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Manual:

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96T

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CLIA Kit for Human Collagen alpha-1(XVIII) chain

Cat.:

U1823m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Collagen alpha-1(XVIII) chain

Cat.:

P1823Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Collagen alpha-1(XVIII) chain

Cat.:

P1823Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Collagen alpha-1(XVIII) chain

Protein for Human Collagen alpha-1(XVIII) chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Complete primary structure of two variant forms of human type XVIII collagen and tissue-specific differences in the expression of the corresponding transcripts."
Saarela J. , Ylikarppa R. , Rehn M. , Purmonen S. , Pihlajaniemi T.
Matrix Biol.16:319-328(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3);VARIANT ILE-1076
2.

"Characterization of the human type XVIII collagen gene and proteolytic processing and tissue location of the variant containing a frizzled motif."
Elamaa H. , Snellman A. , Rehn M. , Autio-Harmainen H. , Pihlajaniemi T.
Matrix Biol.22:427-442(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 1; 2 AND 3);VARIANTS ILE-1076 AND ASN-1675
3.

"The DNA sequence of human chromosome 21."
Hattori M. , Fujiyama A. , Taylor T.D. , Watanabe H. , Yada T. , Park H.-S. , Toyoda A. , Ishii K. , Totoki Y. , Choi D.-K. , Groner Y. , Soeda E. , Ohki M. , Takagi T. , Sakaki Y. , Taudien S. , Blechschmidt K. , Polley A. , more...
Nature405:311-319(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANT ILE-1076
tissue: Kidney.
tissue: PNS.
5.

"Cloning of cDNA and genomic DNA encoding human type XVIII collagen and localization of the alpha 1(XVIII) collagen gene to mouse chromosome 10 and human chromosome 21."
Oh S.P. , Warman M.L. , Seldin M.F. , Cheng S. , Knoll J.H. , Timmons S. , Olsen B.R.
Genomics19:494-499(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1069-1754;VARIANT ARG-1121
6.

"Inhibition effect in vitro of purified endostatin expressed in Pichia pastoris."
Feng Y. , Cui L.B. , Liu C.X. , Ma Q.J.
Sheng Wu Gong Cheng Xue Bao17:278-282(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1568-1754
7.

"Cloning and expression of human endostatin gene in Escherichia coli."
Zhi-Yong H. , Biao L. , Wei-Jie Z. , Xiang-Fu W.
Submitted (1999-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1572-1754;VARIANT ASN-1675
tissue: Placenta.
8.

"Endostatin promotes delayed secondary damage following traumatic brain injury."
Deininger M.H. , Trautmann K. , Schluesener H.J.
Submitted (2001-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1642-1743
9.

"No evidence for locus heterogeneity in Knobloch syndrome."
Aldahmesh M.A. , Khan A.O. , Mohamed J.Y. , Levin A.V. , Wuthisiri W. , Lynch S. , McCreery K. , Alkuraya F.S.
J. Med. Genet.50:565-566(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN KNO1
10.

"Zinc-dependent dimers observed in crystals of human endostatin."
Ding Y.-H. , Javaherian K. , Lo K.-M. , Chopra R. , Boehm T. , Lanciotti J. , Harris B.A. , Li Y. , Shapiro R. , Hohenester E. , Timpl R. , Folkman J. , Wiley D.C.
Proc. Natl. Acad. Sci. U.S.A.95:10443-10448(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 1572-1749;ZINC-BINDING SITE
11.

"Collagen XVIII, containing an endogenous inhibitor of angiogenesis and tumor growth, plays a critical role in the maintenance of retinal structure and in neural tube closure."
Sertie A.L. , Sossi V. , Camargo A.A. , Zatz M. , Brahe C. , Passos-Bueno M.R.
Hum. Mol. Genet.9:2051-2058(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN KNO1
12.

"A polymorphism in endostatin, an angiogenesis inhibitor, predisposes for the development of prostatic adenocarcinoma."
Iughetti P. , Suzuki O. , Godoi P.H. , Alves V.A. , Sertie A.L. , Zorick T. , Soares F. , Camargo A.A. , Moreira E.S. , di Loreto C. , Moreira-Filho C.A. , Simpson A. , Oliva G. , Passos-Bueno M.R.
Cancer Res.61:7375-7378(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ILE-1076 AND ASN-1675
13.

"Knobloch syndrome: novel mutations in COL18A1, evidence for genetic heterogeneity, and a functionally impaired polymorphism in endostatin."
Menzel O. , Bekkeheien R.C.J. , Reymond A. , Fukai N. , Boye E. , Kosztolanyi G. , Aftimos S. , Deutsch S. , Scott H.S. , Olsen B.R. , Antonarakis S.E. , Guipponi M.
Hum. Mutat.23:77-84(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LEU-49; ARG-111; ILE-1076 AND ARG-1121;CHARACTERIZATION OF VARIANT ASN-1675
14.

"DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome."
Ley T.J. , Mardis E.R. , Ding L. , Fulton B. , McLellan M.D. , Chen K. , Dooling D. , Dunford-Shore B.H. , McGrath S. , Hickenbotham M. , Cook L. , Abbott R. , Larson D.E. , Koboldt D.C. , Pohl C. , Smith S. , Hawkins A. , Abbott S. , more...
Nature456:66-72(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ARG-1121

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